Saxenda: what it is for and how to use this medicine

Liraglutide, popularly often called Saxenda, is an injectable drug that is often indicated in instances of kind 2 diabetes, in addition to for overweight sufferers. In the remedy of weight problems, in accordance to pharmacist Andressa Diniz, “saxenda regulates urge for food, reduces meals consumption and, consequently, reduces weight. It additionally regulates thermogenesis, as well as to selling gastric and intestinal motility.

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Medical monitoring is needed for the use of this kind of medicine, as it assesses the affected person’s want for BMI (physique mass index) and if there are different well being issues comparable to diabetes, hypertension, blood problems. fat and obstructive apnea. In addition, weight reduction requires a well-structured meal plan and bodily exercise.

How does this medicine work?

According to the drug producer, liraglutide is comparable to a pure hormone within the physique referred to as GLP-1, which is launched from the intestine after a meal. The drug impacts the receptors of the mind controls urge for food and reduces satiety and starvation.

How to use Saxenda?

Saxenda is an injection to be given beneath the pores and skin (beneath the pores and skin). Your physician or nurse will advise you earlier than utilizing the applying system for the primary time mode of use. It can be utilized at any time of the day, with or with out meals. “The physician will prescribe a dose that can steadily improve over a number of weeks. And its use needs to be related to a low-calorie weight-reduction plan and bodily exercise,” explains Andressa Diniz.

In addition, earlier than utilizing Saxenda, the affected person ought to inform the physician if he is taking different medicines. This is as a result of this kind of medicine delays the emptying of the abdomen and impacts the absorption of medicines when taken collectively.

Using diabetes remedy to drop some pounds

As Andressa Diniz defined, Saxenda was launched in Brazil in 2011 beneath the commerce title Victoza and was used to deal with diabetes. It conquered the anti-obesity market in 2016. This is as a result of after some research, its effectiveness in weight reduction remedy has been confirmed, which has been authorized by the National Health Surveillance Agency (Anvisa).

“Saxenda has turn out to be modern and is being utilized by many individuals with out directions to change it. consuming habits and working towards bodily exercise. In addition, many individuals started to use medication in inadequate doses, inflicting well being dangers. And, like different medication, its use requires warning,” says the skilled.

Yellow pepper, tomato, bottle of water, lettuce and dumbbell in background
The use of the drug needs to be related to weight-reduction plan and bodily exercise.

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Possible negative effects

Like all medicines, liraglutide may cause negative effects, though not everyone will get them. According to Andressa Dean, primary reactions nausea, vomiting, diarrhea and constipation. These signs often disappear after a couple of days or even weeks.

The affected person may have issues affecting the abdomen and intestines, comparable to: indigestion, gastritis, abdomen discomfort, higher abdomen ache, heartburn, bloating, flatulence, sore throat, dry mouth.

Also weak spot or fatigue, adjustments in style, dizziness, insomnia could happen, often within the first 3 months of remedy. Gallstones, injection website reactions (eg, bruising, ache, irritation, itching and rash), hypoglycemia, elevated pancreatic enzymes comparable to lipase and amylase. Other uncommon and uncommon reactions might be discovered within the package deal insert as defined by the pharmacist.


Saxenda is contraindicated in those that are allergic to liraglutide or different parts of the formulation. Also, don’t use whereas breastfeeding. being pregnant and, if planning to turn out to be pregnant, use needs to be discontinued.

“Saxenda is not advisable for use in sufferers with extreme coronary heart failure, severe abdomen or bowel issues that trigger delayed digestion (referred to as gastroparesis), or inflammatory bowel illness. Also in opposition to pancreatitis or irritation of the gallbladder. In addition, it shouldn’t be used on kids beneath 12 years of age or on adolescents weighing 60 kg or much less (between 12 and 18 years of age),” warns Andressa Diniz. In any case, it is finest to seek the advice of your physician earlier than beginning to use it.

*By Andrea Melo

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